Diabetes and depression, a lethal mix

In a meta-analysis and systematic review of 10 studies with a combined 42,363 participants, reviewers found that people with type 1 or type 2 diabetes combined with untreated depression had an increased risk of dying. Four of the studies linked depression to a 20 percent higher risk of cardiovascular-related deaths. 

When depression remains unaddressed, it impacts the likelihood that diabetics will adhere to treatment regimens and maintain healthy habits, which in turn affects both quality of life and the course of the disease.

The authors recommend early detection and treatment of depression to improve the long-term health outcomes of people living with diabetes.

The article, “Depression and risk of mortality in individuals with diabetes: a meta-analysis and systematic review,” was published online on February 15 in General Hospital Psychiatry.