Among the effects of androgen deprivation therapy (ADT) on prostate cancer patients are changes to mental and emotional well-being, according to new research from the University of California San Francisco.
The findings are based on data from the Cancer of the Prostate Strategic Urologic Research Endeavor registry, or CaPSURE, which included more than 3,000 men treated primarily at community-based practices. A quality of life assessment checklist was completed at pretreatment and at least one other time post-treatment.
About 36 percent of patients reported some level of mental impairment before treatment, including depression, sleep disturbances or confusion.
The authors recommend addressing the potential psychosocial impact of ADT with patients, and to minimize its effects before treatment for prostate cancer.
The good news: The study also found that there was no meaningful decline in emotional quality of life two years after completing ADT.
The study appeared in The Journal of Urology.